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Talk with your doctor if you have questions about how drinking alcohol can affect treatment with Topamax. If you have liver problems, such as cirrhosis or hepatitis, you may have an increased risk of high ammonia levels in your blood from taking Topamax. Symptoms can include: feeling agitated, aggressive, or irritable, losing interest in activities you normally enjoy, Ask the tough question: Are you considering suicide?. Or they may recommend switching from Topamax to a different treatment for your condition. anorexia, weight loss, difficulty with memory, taste perversion, diarrhea, hypoesthesia, nausea, abdominal pain and upper respiratory tract . Here we describe a case of carbonation dysgeusia potentially related to the initiation and continued use of topiramate following a generalized seizure. They may suggest medication to manage your symptoms. More common side effects in people taking Topamax for epilepsy include: More common side effects in people taking Topamax to prevent migraine headaches include: * For more information about this side effect, see Side effect specifics below. People with the condition feel that all foods taste sour, sweet, bitter or metallic. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. It can cause side effects that range from mild to serious. a common cold. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. By 4 pm I'm. Just an FYI I didn't start to lose my hair until I was on 150mg of the topamax. 2023 Healthline Media LLC. A patient lost her ability to taste carbonation in all carbonated beverages immediately following topiramate initiation and found that drinking through a straw mitigated the flat taste. These conditions may raise the acid level in your blood. Topiramate was started at a dosage of 25 mg by mouth twice daily and after 3 weeks titrated to a dosage of 100 mg by mouth twice daily for maintenance therapy. See additional information. Swallow the food mixture right away without chewing. Through sensory nerves, the receptors communicate information about tastes to the brain. Learn about common, mild, and serious side effects it can cause and how, Migraine auras are sensory symptoms, including visual disturbances and physical sensations, that occur during or before a migraine episode. Search for other works by this author on: Courtney Doyle-Campbell, PharmD, AHSCP-CHC, Taste and smell disorders in clinical neurology, Drug-related taste disturbance: a contributing factor in geriatric syndromes, Influence of medications on taste and smell, Smell and taste disorders: a primary care approach, Topiramate for migraine prevention: an update, The roles of carbonic anhydrase in gustation, olfaction and chemical irritation, Topiramate for the prophylaxis of episodic migraine in adults, Are migraineurs at increased risk of adverse drug responses? - oh yea - been prescribed this to help prevent seizures. Topamax may cause rare but serious side effects. This includes conditions such as asthma and chronic obstructive pulmonary disease (COPD). Topiramate is a second-generation antiepileptic drug that is used in the treatment of seizure disorders and migraine headaches.7 Its use has been associated with weight loss; nausea and other gastrointestinal adverse effects; paresthesia in the hands, feet, or face; and cognitive and behavioral changes, including memory impairment, confusion, and reduced concentration. And your doctor can use this information to adjust your treatment plan if needed. Uses. I've been on Topamax for two months and I still can't stand to smell food, or taste what I eat or drink. The pain can be so severe that it becomes debilitating. Additionally, missing too many doses of Topamax (or suddenly stopping the drug) may increase the risk of seizures. This medication is also used to prevent migraine headaches and decrease how often you get . In theory, because carbonic anhydrase is a zinc metalloenzyme, administration of carbonic anhydraseinhibiting medications may lead to zinc deficiency and, ultimately, taste distortions. Your comment will be reviewed and published at the journal's discretion. It may sometimes cause side effects, especially if you misuse it. Learn about the drugs dosages, forms, and more. Before taking Topamax, tell your doctor if you have bone problems such as osteoporosis. Hair loss from Topamax is generally reversible. However, it isnt known how often this side effect may have occurred in clinical trials. You should not drink alcohol while youre taking Topamax. Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Or they may suggest you wean off Topamax and try a different treatment for your condition. Topamax (topiramate) is a prescription drug that's used to treat epilepsy and help prevent migraine headaches. It is just as hard coming off this drug as it is going on it. Official answer. "Thankfully, this is normally a temporary problem," Dr. Kaye says. Or it may include a topical product (thats applied to your skin), such as hydrocortisone cream. This type of diet may raise the level of acid in your blood. They can help answer any questions you have about side effects from taking the drug. Can diet help improve depression symptoms? Diarrhea. bleeding. Ocular (eye-related) side effects may occur with Topamax. This side effect wasnt common in clinical trials and was only reported by people taking the drug for epilepsy. Najafizade et al24 demonstrated that zinc supplementation increased perception of all sweet, sour, bitter, and salty tastes among patients with head or neck cancer undergoing radiotherapy. In this line of thought, zinc supplementation may be needed with carbonic anhydrase inhibitor administration to prevent or treat dysgeusia. Topamax may also affect weight and height in children taking the drug. They can help you figure out if youre having other mood changes that could cause these side effects. If you have questions about Topamax and hair loss, talk with your doctor or pharmacist. Which can be very dangerous and just plain weird. "Local trauma" to the tastebuds aka burning your tongue on hot stuff can change your sense of taste. How long does it take for Topamax to start working? Case assessment using the adverse drug reaction probability scale of Naranjo et al15 indicated a probable relationship between topiramate use and carbonation-perception loss (ie, a score of 5). If untreated, this condition can lead to bone problems, including osteoporosis (weakened bones). Cookie Notice We comply with the HONcode standard for trustworthy health information. She was also experiencing mild hand and feet paresthesia, which are commonly reported adverse effects of the medication.14 Bloodwork performed 10 months after topiramate initiation indicated that all values were within normal limits, with the exception of a low alkaline phosphatase (ALP) level (38 U/L [reference range, 50-136 U/L] and low creatinine concentration (0.7 mg/dL [reference range, 0.8-1.3 mg/dL]; neither low value was deemed concerning. 1 more week and I'm finished. By using our website, you consent to our use of cookies. 1. These problems include chronic obstructive pulmonary disease (COPD). If I have side effects from Topamax, will I need to take a lower dose of the drug? And if untreated, glaucoma could cause blindness. Talk with your doctor to learn if Topamax is right for you. Possibly. Medication-related changes in taste are important to identify because such changes can negatively affect medication adherence, chronic disease management, and overall quality of life. Your doctor may prescribe a temporary treatment to help you manage these side effects for a short period of time. But Topamax can also cause serious side effects in some people, especially at higher doses. In clinical trials, how often certain side effects occurred varied depending on which dose of Topamax was taken. After initiation of topiramate therapy, the patient began to experience an immediate change in her carbonation perception when drinking carbonated beverages; all carbonated beverages, including seltzer and beer, tasted flat. The patient remained on topiramate for the subsequent 12 months without her carbonation perception returning to normal but noted that drinking carbonated beverages through straws slightly mitigated the adverse effect. What are the serious side effects of Topamax? I do not think it is the same for seizure treatment. Although rare, treatment with Topamax can cause a condition called secondary closed-angle glaucoma. If youve had an allergic reaction to Topamax or any of its ingredients, you should not take Topamax. Specifically, Topamax is used in adults and some children to: The active ingredient in Topamax is topiramate. Folic acid is also a great supplement. Oh, yeah. Get answers from Cardiologists and top U.S. doctors, Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care. The brain fog was really bad at first. Although rare, Topamax can also cause a glaucoma attack. BUT, I've taken the damn vaccine and I still wear my mask and I'm antisocial and have social anxiety so I don't even go outside and if I do (to walk my service dog) I stay away from people AND I STILL WEAR MY DAMN MASK so I kept thinking 'how on earth could I have gotten covid if I'm never around people. Its possible. If you are not in the same household, stay on the phone with them until help arrives. Topamax (topiramate) tablets, for oral use; Topamax (topiramate capsules) sprinkle capsules, for oral use. I know topamax (topiramate) for migraine also works as appetite suppressant, but what is the chemical reason? It may not be safe to take Topamax while pregnant. Dunkel and Hofmann also suggested that carbonic anhydrase 4, specifically, mediates the fizzy sensation experienced on drinking carbonated beverages. Symptoms of these conditions may include: Tell your doctor right away or go to the nearest emergency room if you notice any of the above symptoms while youre taking Topamax. Topamax doesnt rely heavily on your liver to help remove it from your body. Your doctor may suggest a different seizure diet for you while youre taking Topamax, if needed. Stay with the person until professional help arrives. You should not take Topamax if youve ever had an allergic reaction to Topamax or any of its ingredients. I must be the only one with this crazy list, so I thought I would share! But again, it sounds like over 50% of people take topomax with great results. Learn. Ask your doctor what other medications are better options for you. You can also see Topamaxs prescribing information or talk with your doctor or pharmacist. Most of the participants did lose weight while on the drug, significantly more than the placebo group, however, the side effects discouraged some from continuing the trial. So it may be hard for you to tell if sexual side effects are caused by Topamax itself or by certain mood changes the drug may cause. An allergic reaction is possible after using Topamax. And do not stop using Topamax unless your doctor recommends it. Examples include: If you have more questions about your risk of certain side effects from Topamax, talk with your doctor or pharmacist. These side effects may be temporary, lasting a few days or weeks. Ohhhh Topamax. Your doctor may monitor your acid levels more closely than usual during treatment. So I've been on Topamax since around September and I've only lost like 3 lbs unfortunately lol. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. American Society of Health-System Pharmacists 2020. And all food tasted weird, exept for garlic for some reason. For the most part, side effects of Topamax in children are similar to those in adults. Lung problems. I just started on Topamax (topiramate), (topiramate) but I've gotten a headache today that doesn't seem to want to go away. Or you may notice a metallic or unusual taste in your mouth. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. They can suggest ways to maintain a weight thats healthy for you. and our These symptoms could be life threatening and require immediate medical care. However, I'm really losing weight. I will be building up to eventually be at 100 mg twice a day will this side effect go away? For example, the following side effects were more likely to happen with higher doses (200 mg) of Topamax (compared with 25 mg or 50 mg, for example): For details about side effects in studies, you can see Topamaxs prescribing information. If you or someone you know is in crisis and considering suicide or self-harm, please seek support: If youre calling on behalf of someone else, stay with them until help arrives. Why does the taste of topamax (topiramate) stay in my mouth and how can I get it out? Department of Pharmacy Practice, Western New England University College of Pharmacy and Health Sciences, Address correspondence to Dr. Charbonneau (. One was the bad taste in my mouth all the time. Besides talking with your doctor, you can do some research on your own. Examples include hair. They both tasted just fine before I started on topamax. I've been on Topamax for six months now for chronic daily headache, slowly escalating to a dose of 150 mg every night. You may need blood tests to make sure the level of acid in your blood is safe. Topamax can cause shifts or changes in mood, including suicidal thoughts. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. More common side effects in people taking Topamax for migraine include: More common side effects in people taking Topamax for epilepsy include: Read on to learn about other mild and severe side effects that can happen with Topamax. ', Can someone tell me if I will ever enjoy Coca Cola ever again? Your doctor can help determine whether treatment with Topamax is safe for you. Following a ketogenic (keto) diet can increase acid levels in your blood. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Forgetting stuff at the grocery store, where I put my keys, stuff like that. Here are some frequently asked questions about the drugs side effects and their answers. It can lead to blindness if its not treated. Mild side effects that have been reported with Topamax include: burning or numbness in your hands and feet appetite loss speech problems fatigue dizziness * sleepiness nervousness memory. If you have side effects that wont go away or are hard to deal with, your doctor will likely have you wean off Topamax. Started topamax (topiramate) about 4 days ago and everything i eat runs right through me. Please check for further notifications by email. Not to mention it took that long for the word slurring feeling and brain fog to go away. A bitter or bad taste in the mouth can occur after eating pungent or sour foods, but it can also stem from hormonal changes, poor oral health, medication use, stress, and many other factors. Yes, the risk of side effects from Topamax can depend on the strength you take. Never disregard or delay professional medical advice in person because of anything on HealthTap. Its also important to know that suddenly stopping Topamax could cause or worsen seizures. Topamax is a brand-name prescription medication that's FDA-approved in certain situations to: Prevent migraine headaches in adults as well as children ages 12 years and older. Below are a few of the more common side effects reported by people who took Topamax in studies. Is that a side effect? Topamax can be prescribed for weight loss. Carbonic anhydrase is a zinc metalloenzyme that reversibly catalyzes the conversion of carbon dioxide (CO2) and water into carbonic acid (H2CO3), which rapidly dissociates to bicarbonate (HCO3-) and a free proton.18 Carbonic anhydrase inhibitors, such as acetazolamide and dorzolamide, prevent this conversion and have been reported to alter carbonation taste perception.19 In one reported case, after taking acetazolamide to prevent altitude sickness mountain climbers noted that their beer tasted like dishwater.20 Another case report described a 31-year-old woman who took acetazolamide to prevent mountain sickness and, within 90 minutes, developed a bitter taste sensation on consuming carbonated soda, tea, and Mexican food.21 The symptoms resolved within 14 hours after acetazolamide discontinuation. Your doctor can help determine whether treatment with Topamax is safe for you. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. For me (i was eventually on 250 mg for migraines) every time I increased my dose I had those symptoms for about 2 or 3 days and then would subside until my next increase.I did discuss the anxiety with my Dr. and he prescribed xanax which helped a lot. Before taking Topamax, tell your doctor if you have mood problems such as depression. You can learn more about how we ensure our content is accurate and current by reading our. You can learn more about how we ensure our content is accurate and current by reading our. Keep reading to learn about the common, mild, and serious side effects of Topamax and ways to deal with them. I also lost abut 1/3 of my hair. Do the side effects of topamax (topiramate) go away while taking it? If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. Call your doctor if you have changes in taste while taking Topamax. Mild side effects from Topamax are common. Below we provide information about Topamax and pregnancy and breastfeeding. Mild side effects can occur with Topamax use. If taken while breastfeeding, Topamax may pass into breast milk. Youll likely take Topamax long term if you and your doctor agree that its working well for you. Serious side effects that have been reported with Topamax include: If you develop serious side effects while taking Topamax, call your doctor right away. Last medically reviewed on October 25, 2022, Trokendi XR, which is used for epilepsy and migraine, can cause side effects such as weight loss. Topamax is also commonly used to prevent migraine headaches in adults. Some of these side effects are mild, while others can be more serious. 7 Its use has been associated with weight loss; nausea and other gastrointestinal adverse effects; paresthesia in the hands, feet, or face; and cognitive and behavioral changes, including memory impairment, confusion, This measurement describes bone strength. ? In most cases, side effects from Topamax are temporary. If youd like to notify the FDA about a side effect youve had with Topamax, visit MedWatch. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. a stuffy and runny nose. The serum topiramate concentration was determined 17 days after topiramate initiation, 3 days after a dosage increase to 75 mg twice daily, and was considered to be in the therapeutic range, at 6.2 g/mL (reference range, 5-20 g/mL). In Savoie in Bisanne 1500, on the Domaine des Saisies Espace Diamant, 3-room apartment with an area of 40 m2 on the ground floor + balcony + covere. That tingle feeling and digestion issues are super common with topomax withdraw. Tell your doctor if you have lung problems before starting Topamax. It all tastes weird & just bad, like an awful stinging, metallic taste on my tongue. Learn more about some of the side effects Topamax may cause. If a child takes Topamax, their doctor will check their growth. You should always consult your doctor or another healthcare professional before taking any medication.
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